Dr. Lydia Colaco B.A., M.D., D.G.O., F.R.C.S., M.R.C.O.G., started the COLACO HOSPITAL, a unit of I.C.M.C.H Trust in the year 1957. She was South India's highest qualified lady medical practitioner. The Hospital is the first private hospital of Mangalore. In her career spanning 50 years, she conducted more than 25,000 child deliveries, most of which were challenging. Her dedication, talent and fame spread across the Konkan and Malabar Coast. In her twilight years she donated the Hospital complex to the Isidore Colaco Memorial Charitable Hospital Trust. The hospital is now a 200 bedded, state of the art multi speciality unit with a built up area of 40,000 sq.ft spread over 22,000 sq.ft of land on Bendore Main Road, in the heart of the city. The main objective of the trust is to extend health services to the maximum number of people at the most reasonable rates and to spread education with special emphasis on the girl child.

With the increasing demand for well-trained, qualified and spiritually inclined Nurses, Colaco Hospital has started 3 ½ years Revised General Nursing & Midwifery Course from 2003 and is situated at Kankanady which is in the heart of the picturesque city of Mangalore, with a built up area of 28,000 Sq.ft. Colaco School of Nursing is fully owned by the Isidore Colaco Memorial Charitable Hospital Trust. Railway Station is just at a distance of 2 kms from the school.